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Evergreen Herbs Palo Azul 8 oz. - Kidney Wood, Eysenhardtia Polystachya, Blue Stick, Wild Crafted, Great for Detox - Resealable Stand Up Pouch to Ensure Freshness!

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When the EP/AgNPs were treated with SIF at pH 6.8 or 7.4, EP release was also time dependent; at 4 h, the amount of drug released was higher than that obtained at pH 1.2, and continuous prolonged release of 75%–88% of the initial amount of EP until 10 h was observed. This could be due to the interaction between the alkaline solvent and the positive charges of the EP compounds. Based on these results, we assume that sustained release is due to the diffusion of EP through the system and that release was regulated in a pH-dependent manner. Narváez-Mastache, J.M.; Garduño-Ramírez, M.L.; Alvarez, L.; Delgado, G. Antihyperglycemic activity and chemical constituents of Eysenhardtia platycarpa. J. Nat. Prod. 2006, 69, 1687–1691. [ Google Scholar] [ CrossRef]

Alarcon-Aguilar, F.J.; Roman-Ramos, R.; Pérez-Gutierrez, S.; Aguilar-Contreras, A.; Contreras-Weber, C.C.; Flores-Saenz, J.L. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J. Ethnopharmacol. 1998, 61, 101–110. [ Google Scholar] [ CrossRef] In this study, we describe the synthesis of AgNPs using water/methanol extract (EP) of E. polystachya. Synthesized EP/AgNPs were characterized using various analytical methods. Nanoparticles did not present agglomeration and were uniform, and most of them were spherical, with a size range of 5–21 nm. Synthesized AgNPs was found to be very stable for over a year without the addition of any stabilizer. The water/methanol extract (EP) of E. polystachya was previously fractionated by several chromatographies. 31, 32 Then, the bioactive components were isolated, and their chemical structure determined to be chalcones, dihydrochalcones, and flavonoids (data not shown).Aggarwal, A.; Singla, S.K.; Tandon, C. Urolithiasis: Phytotherapy as an adjunct therapy. Indian J. Exp. Biol. 2014, 53, 103–111. [ Google Scholar]

The amount of total flavonoids in the EE and its fractions was measured by a colorimetric assay according to the method of Lamaison and Carnet ( 16), with some modifications. The anti-arthritic and antinociceptive mechanisms of the bark of Eysenhardtia polystachyaare not yet known. Flavonoids could be responsible, but other chemicals could be equally important such as coumarins, quinones, saponins, and tannins. These phytochemicals have antiphlogistic and antinociceptive activities in other plant species ( 9, 30). An ethnobotanical study of ethanol extracts obtained from various medicinal plants used in the Mexican traditional medicine to treat oral bacterial diseases showed that kidneywood was among those that exhibited the highest in vitro inhibitory effect against the bacterial species Streptococcus mutans and Porphyromonas gingivalis (Rosas-Piñón et al., 2012).Abbreviations: EP, Eysenhardtia polystachya extract; AgNPs, silver nanoparticles; EP/AgNPs, Eysenhardtia polystachya-loaded silver nanoparticles.

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